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Journal of Drug Research in Ayurvedic Sciences 2023 April - June ; 8 (2) :150 -158
Pharmacognostical and pharmaceutical analysis of Jeevantyadi Avaleha: A polyherbal Ayurvedic formulation

Abstract
BACKGROUND: Good prenatal care includes the mother’s nutrition and healthy habits during pregnancy. Failure to supply adequate nutrition can lead to fetal malnutrition. Critical analysis of the dietetic guidelines mentioned in Ayurveda classics for pregnancy reveals that the recommended diet has Rasayana (rejuvenation) properties, which covers the additional nutritional needs. Jeevantyadi Avaleha is a formulated combination (Anubhoot yoga) of Jeevanti, Shatavari, Amalaki, Guduchi, Atibala, Draksha, Arjuna, and Sita; almost all of these have Sheeta veerya (cold potency), Madhura vipaka (sweet bio-transformed rasa) and Rasayana property. To properly evaluate the finished product from the perspectives of safety, efficacy, and quality, pharmacognostic and pharmaceutical analyses were done. METHODS: Jeevantyadi Avaleha was prepared after identification, authentication, and microscopic evaluation of raw drugs as per the standards mentioned in Ayurvedic Pharmacopoeia of India. In pharmacognostical evaluation, organoleptic study and microscopy were done. In pharmaceutical evaluation, physicochemical analysis and high-performance thin layer chromatography (HPTLC) were carried out. Physicochemical parameters namely loss on drying, pH value, water-soluble extract, and alcohol-soluble extract were tested. RESULTS: The diagnostic features obtained by microscopy were compared with the standards of the individual drugs mentioned in Ayurvedic Pharmacopoeia of India. On HPTLC of the formulation, five spots were visualized at ultraviolet 254?nm and three spots at ultraviolet 366?nm. CONCLUSION: After assessing the pharmacognostical parameters, Jeevantyadi Avaleha was found to be genuine. This study’s results may be considered as the reference standard in future research proceedings. Keywords: Jeevantyadi Avaleha, pharmacognosy, pregnancy, Rasayana

DHARA ID: D060895


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