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Journal of Drug Research in Ayurvedic Sciences 2022 October - December ; 7 (4) :213 -220
A narrative literary review on design of anti-diabetic (Prameha) formulations from various Ayurveda treatises

Abstract
Ayurveda texts spanning from 100 BC to 18th AD, which have not been frequently scrutinised for management of Prameha (Diabetes mellitus) have been selected. This review is expected to enrich the documentary evidences about classical references on formulations related to Prameha (Diabetes mellitus) as add on to future researches. A total of 524 formulations out of 15 Ayurveda texts have been considered to observe drug design methods in this review paper. Formulations with Phalashruti (verse with indications) of “Prameha” were scrutinised. The preliminary data was categorised based on their dosage forms, indications of formulations in accordance to Doshas (regulatory functional factors of the body), adjuvants etc and the result have been substantiated. Drugs and formulations most enumerated amongst these 15 texts have been presented. Kwatha (decoction) is most enumerated dosage form (241 formulations). Honey is most enumerated adjuvant (172 formulations). Nyagrodadhi gana (kwatha or churna) and Dhanvantara ghrita were the most frequently mentioned formulation. Triphala was the most enlisted drug amongst 323 formulations (in formulation with less than 10 ingredients). Vidanga (Embelia ribes Burm.f.), Arjuna (Terminalia arjuna (Roxb.) Wight and Arn.) Patha (Cissampelos pareira L.) were most repeated drugs indicated in Kaphaja Prameha, Pittaja Prameha and Vataja Prameha respectively (in formulation with less than 10 ingredients). This review gives comprehensive detail related to formulations indicated in Prameha (Diabetes mellitus) compiled from 15 Ayurveda treatises. Keywords: Ayurveda, diabetes mellitus, formulations, Prameha

DHARA ID: D060870


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