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Journal of Drug Research in Ayurvedic Sciences 2022 April- June ; 7 (2) :97 -104
First-order kinetic study-based comparative shelf-life assessment of Raw Vetas (Salix alba L. stem bark) and Vetas Ghana (a semisolid form of Salix alba L. stem bark aqueous extract)
Ravi Verma (1), Vipin Jain (1), Hemant Rawat (1), Vikram Kushwaha (1), Yashika Gandhi (1), Sujeet K Mishra (1), Vijay Kumar (1), Smriti Tandon (2), Vaibhav Charde (3), Chandrashekar Jagtap (3), Gajji Babu (4), Arjun Singh (5), Ravindra Singh (5), Bhagwan Sahai Sharma (6), Narayanam Srikanth (6)
1. Department of Chemistry, Central Ayurveda Research Institute, Jhansi, Uttar Pradesh, India 2. Department of Microbiology, Central Ayurveda Research Institute, Jhansi, Uttar Pradesh, India 3. Department of Ayurveda, Central Ayurveda Research Institute, Jhansi, Uttar Pradesh, India 4. Department of Ayurveda, Central Ayurveda Research Institute, Jhansi, Uttar Pradesh, India 5. Department of Chemistry, Central Council for Research in Ayurvedic Sciences, New Delhi, India 6. Department of Ayurveda, Central Council for Research in Ayurvedic Sciences, New Delhi, India
Abstract
BACKGROUND: Shelf-life is an important aspect of raw as well as finished drugs. Recently, shelf-life parameters have been included in the Ayurvedic Pharmacopeia of India (API). The aim of this study to evaluate the comparative long-term shelf-life study of Raw Vetas (Salix alba stem bark) and Vetas Ghana (a semisolid form of Salix alba Stem bark aqueous extract). METHODS: A stability chamber with environmental conditions 30°C ± 2°C/60% RH ± 5% was used for the long-term shelf-life study of Raw Vetas and Vetas Ghana. Physicochemical parameters like loss on drying, pH, total ash, acid insoluble ash, water extractive value, and alcohol extractive value were evaluated at a regular frequency (0th, 3rd, 6th, 9th, and 12th months). RESULTS: There are significant changes that have been observed w.r.t. physicochemical parameters analysis. Physicochemical parameters revealed that the shelf-life of Raw Vetas ranged from 31 to 66 months and the shelf-life of Vetas Ghana ranged from 38 to 62 months. CONCLUSIONS: The average shelf-life of Raw Vetas and Vetas Ghana was 41.83 and 47.50 months, respectively. This study may help to understand the shelf-life of various Ayurvedic formulations consisting of Raw Vetas and Vetas Ghana. Keywords: API, Salix alba, shelf-life, Vetas, Vetas Ghana
DHARA ID: D060854
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