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Journal of Drug Research in Ayurvedic Sciences 2022 January- March ; 7 (1) :47 -54
Comparative shelf-life study of Raw Guggulu (Commiphora wightii oleo-gum resin) and Shodhita Guggulu (cow urine processed C. wightii oleo-gum resin)
Vaibhav Charde (1), Chandrashekar Jagtap (1), Gajji Babu (1), Vijay Kumar (2), Vikram Kushwaha (2), Jyotika Grewal (2), Sujeet K Mishra (2), Santosh K Shakya (2), Hemant Soni (3), Gagandeep Singh (3), Arjun Singh (4), Ravindra Singh (4), Shruti Khanduri (4), Bhagwan Sahai Sharma (5), Narayanam Srikanth (5)
1. Department of Ayurveda, Central Ayurveda Research Institute, Jhansi, Uttar Pradesh 284003, India 2. Department of Chemistry, Central Ayurveda Research Institute, Jhansi, Uttar Pradesh 284003, India 3. Department of Microbiology, Central Ayurveda Research Institute, Jhansi, Uttar Pradesh 284003, India 4. Department of Chemistry, Central Council for Research in Ayurvedic Sciences, New Delhi, India 5. Department of Ayurveda, Central Council for Research in Ayurvedic Sciences, New Delhi, India
Abstract
BACKGROUND: Shelf-life is an important aspect of raw as well as finished drugs. Recently, shelf-life parameters have been included in the Ayurvedic Pharmacopeia of India. The objective of this article is to evaluate and compare the long-term shelf-life study of Raw Guggulu (RG) (C. wightii oleo-gum resin) and Shodhita Guggulu (SG) (cow urine processed C. wightii oleo-gum resin). MATERIALS AND METHODS: A stability chamber with environmental conditions 30°C ± 2°C/60% ± 5% RH was used for long-term shelf-life study of RG and SG. Physico-chemical parameters such as loss on drying, pH, total ash, acid-insoluble ash, water extractive value, and alcohol extractive value were tested at regular frequency (0th, 3rd, 6th, 9th, and 12th month). RESULTS: Significant changes have been observed w.r.t. analysis of physico-chemical parameters. Physico-chemical parameters revealed that the shelf-life of RG ranged from 42 to 66 months and shelf-life of SG ranged from 39 to 62 months. CONCLUSION: The average shelf-life of RG and SG was found out to be 55.16 and 48.16 months, respectively. These studies may help to understand the shelf-life of various ayurvedic formulations of RG and SG. Keywords: API, Commiphora wightii, resin, shelf-life, Shodhita Guggulu
DHARA ID: D060847
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