Home | About | Quick Start | FAQ
Beta Version 0.1
DHARA is an online index of articles on Ayurveda published in research journals worldwide. Users Online: 2949
  Enter Keyword Below :
      
Advanced

Journal of Drug Research in Ayurvedic Sciences 2019 July- September ; 4 (3) :113 -118
Evaluation of Antihyperglycemic and Hypoglycemic Activities of Shadguna Makaradhwaja and Guduchi Ghana in Swiss Albino Mice

Abstract
Background: Diabetes mellitus (DM) is a group of metabolic disorders which share the common phenotype of hyperglycemia that occurs due to defects in insulin secretion, insulin action, or sometimes both. Herbomineral formulations can be the alternative for contemporary synthetic oral hypoglycemic agents due to their potency, suitability, and negligible side effects. Makaradhwaja is one of those potent antidiabetic drugs used in Ayurved. Objectives: To evaluate the hypoglycemic and antihyperglycemic activity of Shadguna Makaradhwaja (SM) formulations prepared by Swarna Varkha (SMV) and from residue Apakwa Talastha Swarna powder (SMR) with Guduchi Ghana (GG) in Swiss albino mice. Materials and methods: Oral glucose tolerance test and 18 hours fasted mice model were used. Shadguna Makaradhwaja with GG (5.85:94.15 ratios) was administered with honey at a dose of 65 mg/kg. Glibenclamide (GB; 0.65 mg/kg) was used as the standard drug. Results: In hypoglycemic study, SMV showed 18.2, 27.83, 34.88, and 47.41%, while SMR showed 4.85, 20.52, 29.70, and 44.3% reduction in blood sugar level (BSL) at 1, 2, 3, and 5 hours, respectively. In antihyperglycemic study, SMV showed 81.73, 49.23, 14.8, and 0% and SMR showed 56.38, 42.23, 1.16, and 21.58% reduction in BSL at 30, 60, 90, and 120 minutes, respectively. Both results were statistically significant when compared to the control group. Conclusion: Test drugs showed significant hypoglycemic and antihyperglycemic effects as compared to the control group. SMV showed more hypoglycemic effect, while SMR showed better antihyperglycemic effect. Keywords: Ayurved, Diabetes mellitus, Herbomineral, Makaradhwaja, Rasashastra

DHARA ID: D060779


Link To Full Paper

Replica Louis vuitton Belts Replica Louis vuitton Handbags Replica Louis vuitton Backpack Replica Louis vuitton Capucines Bags Imitazioni Louis vuitton Borse Imitazioni Louis vuitton Cinture Imitazioni Louis vuitton Occhiali Replica Louis vuitton Geldb?rsen Replica Louis vuitton Gürtel Replica Louis vuitton Schmuck Replica Louis vuitton Schal Imitation Louis vuitton Bijoux Imitation Louis vuitton Ceinture Imitation Louis vuitton Chaussures Imitation Louis vuitton Foulard namaak Louis vuitton Gordels namaak Louis vuitton Handtassen namaak Louis vuitton Portemonnees namaak Louis vuitton Schoenen Replica Louis vuitton Bolsos Replica Louis vuitton Billeteras Replica Louis vuitton Cinturones Dior Replica Hermès Replica Yves Saint Laurent Replica Goyard Replica Imitation Louis Vuitton Imitation Hermès Imitation Dior Imitation Yves Saint Laurent Imitazioni Bottega Veneta Borse Imitazioni Delvaux Borse Imitazioni Goyard Borse Replica Taschen Replica Louis Vuitton Replica Hermès Replica Dior Replica Bottega Veneta tassen Replica Chloé tassen Replica Delvaux tassen Replica Goyard tassen imitacion Louis Vuitton imitacion Louis Vuitton imitacion Hermès imitacion Dior Replica Miu Miu Replica Prada Replica Yves Saint Laurent Replica Chanel Replica Gucci Replica Hermès Replica Miu Miu Réplique Chanel Réplique Hermès Réplique Miu Miu Imitazioni Chanel Imitazioni Hermès Imitazioni Miu Miu imitacion Bolso Yves Saint Laurent imitacion Hermes imitacion Chanel imitacion Gucci Gucci Replica Hermes Replica

Copyright | Disclaimer | Feedback | Updates | Contact
Developed and maintained by AVP Research Foundation (Formerly AVT Institute for Advanced Research), 136/137, Trichy Road, Ramanathapuram, Coimbatore - 641045, Tamil Nadu, India
Funded by Central Council for Research in Ayurvedic Sciences, Dept. of AYUSH, Ministry of Health and Family Welfare, Government of India, New Delhi