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Journal of Research in Ayurvedic Sciences 2019 April - June ; 3 (2) :64-67
Safety and Efficacy of Ayurvedic Interventions in the Management of Conjunctivitis: A Protocol for a Systematic Review

Abstract
2% of the population. Conventional treatment has many options for treating the disease. Despite adequate treatment options, patients continue to suffer troublesome symptoms. Complementary and alternative medicine (CAM) therapies may play a significant role here. Systematic reviews on this topic have been published for herbal medicines. Data are available on plenty of studies individually proving efficacy and safety of various Shodhana, Shamana, and Netra Kriyakalpa in conjunctivitis. However, systematic review of Ayurveda interventions for conjunctivitis is unavailable. This study aims at a thorough review of published clinical data of safety and efficacy of Ayurvedic interventions in the management of conjunctivitis. Materials and methods: A systematic review of randomized controlled trials (RCTs), quasi-randomized controlled trials (QRCTs), controlled clinical trials (CCTs), and multiple arms clinical trials on conjunctivitis published till date will be conducted. Studies having patients fulfilling the diagnostic criteria based on the symptomatology of Abhishyanda (HF-1) explained in classic Ayurveda texts and conjunctivitis of all ages and either sex will be included. Studies in which Ayurvedic treatments (Shamana, Shodhana, or/and Netra Kriyakalpa) with any dose, type, schedule, drug, dosage form, and advised Pathayapathya (lifestyle changes) as intervention or control will be selected. The primary outcome will be the response to treatment and onset of serious adverse events. Ethics and dissemination: Formal ethical approval will be obtained. The results will be disseminated through a peer-reviewed publication. Trial registration number: International prospective register for systematic reviews (PROSPERO) number CRD42019129436. Keywords: Ayurveda, Conjunctivitis, Efficacy, Protocol for a systematic review, Safety

DHARA ID: D059620


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