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Journal of Research in Ayurvedic Sciences 2017 July- September ; 1 (3) :131-135
Clinical Observation of Haridrakhanda in the Management of Sheetapitta with respect to Urticaria: A Retrospective Cohort

Abstract
Introduction: In the present era, one inevitably meets with various causes of Dhatu-daurbalya (disturbed immune system), which lead to various allergic diseases like urticaria— a type I hypersensitivity reaction that can be compared with Sheetapitta mentioned in Ayurveda. Although the disease is not life-threatening, it makes the patient troubled due to severe itching and its long-lasting tendency. Aims and objectives: To observe safety and efficacy of Haridrakhanda in the patients suffering from Sheetapitta (urticaria) in the clinical setting. Materials and methods: An observational retrospective cohort design was adopted for the study. Patients of either sex, suffering from urticaria, of age between 18 and 70 years, were selected from the outpatient department (OPD) of Regional Ayurveda Research Institute for Nutritional Disorders (RARIND), Central Council of Research in Ayurvedic Sciences (CCRAS), Mandi, Himachal Pradesh, India, from March 2013 to June 2014. The patients who were treated with Haridrakhanda in the dose of 3 gm twice a day with milk for 14 days and who have shown 100% compliance of medicine were only considered for study. Following Ayurveda clinical symptoms of Sheetapitta were observed: Varati Dashta Samsthana Shotha (inflammation rash, like an insect bite), Kandubahulya (severe itching), Todabahulya (severe pricking pain), Raga (redness of skin), Vidaha (burning sensation), Chhardi (vomiting), and Jwara (fever) with grading of 0 (absent), 1 (mild), 2 (moderate), and 3 (severe). Results: Neither any concomitant medication was used nor was any adverse effect reported or noticed during the study. At the end of day 14, all 39 patients experienced improvement, maximum in Toda (pain) followed by Kandu (itching) and Varati Dashta Samsthana Shotha (swelling). Statistically significant improvement was found in all signs and symptoms (p<0.001). Conclusion: Haridrakhanda was found safe and effective in the management of Sheetapitta. This study may be considered as a primary evidence for further studies on large sample size to consolidate the results. Keywords: Allergy, Ayurveda, Dhatu-daurbalya, Hypersensitivity reaction.

DHARA ID: D059567


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