Home | About | Quick Start | FAQ
Beta Version 0.1
DHARA is an online index of articles on Ayurveda published in research journals worldwide. Users Online: 81
  Enter Keyword Below :
      
Advanced

Journal of Research in Ayurvedic Sciences 2017 April - June ; 1 (2) :108 - 116
Clinical Safety of Selected Ayurvedic Formulations in Rheumatoid Arthritis

Abstract
Introduction: Rheumatoid arthritis (RA) is a chronic systemic autoimmune inflammatory disease which mainly affects the small joints leading to erosion of cartilage and bone associated with irreversible joint damage, joint deformity, and systemic complications. The symptoms of RA resemble with the signs and symptoms mentioned in Amavata described in different texts of Ayurveda. Simhanada Guggulu, Brihat Saindhavadya Taila, Vatari Guggulu, Rasna Saptaka Kashaya, and Hingvashtaka Churna are commonly used in the management of this disease. However, the safety data are not collected on these formulations till now. Objective: Critical analysis and presentation of clinical safety outcomes of classical Ayurvedic formulations Simhanada Guggulu, Brihat Saindhavadya Taila, Vatari Guggulu, Rasna Saptaka Kashaya, and Hingvashtaka Churna in patients of RA generated for Research in Ayurvedic Sciences (CCRAS) centers. Materials and methods: Data were collected from three different clinical studies executed in peripheral institutes of CCRAS and were critically evaluated to assay the safety profile of five formulations. Safety assessments were done through analyzing liver function tests (LFTs) and kidney function tests (KFTs) before and after the study trial period. Conclusion: The findings in the three different clinical studies clearly indicate that Simhanada Guggulu, Brihat Saindhavadya Taila, Vatari Guggulu, Rasna Saptaka Kashaya, and Hingvashtaka Churna are clinically safe and tolerable in the participants belonging to different age groups, gender, geographical area, and different prakrti. Keywords: Amavata, Brihat Saindhavadya Taila, Hingvashtaka Churna, Rasna Saptaka Kashaya, Rheumatoid arthritis, Safety, Simhanada Guggulu, Vatari Guggulu.

DHARA ID: D059562


Link To Full Paper

Copyright | Disclaimer | Feedback | Updates | Contact
Developed and maintained by AVP Research Foundation (Formerly AVT Institute for Advanced Research), 136/137, Trichy Road, Ramanathapuram, Coimbatore - 641045, Tamil Nadu, India
Funded by Central Council for Research in Ayurvedic Sciences, Dept. of AYUSH, Ministry of Health and Family Welfare, Government of India, New Delhi