Home | About | Quick Start | FAQ
Beta Version 0.1
DHARA is an online index of articles on Ayurveda published in research journals worldwide. Users Online: 738
  Enter Keyword Below :
      
Advanced

Natural Product Research 2015 Apr :0
Attenuating effect of bioactive coumarins from Convolvulus pluricaulis on scopolamine-induced amnesia in mice.

Abstract
Convolvulus pluricaulis Chois. (Convolvulaceae) has been used in Ayurveda as Medhya Rasyana (nervine tonic) to treat various mental disorders. This study was designed to isolate the bioactive compound(s) of this plant and to evaluate their effect against scopolamine-induced amnesia. Column chromatography of the chloroform and ethyl-acetate fractions led to the isolation of three coumarins identified as scopoletin, ayapanin and scopolin. All the three compounds at 2.5, 5, 10 and 15 mg/kg, p.o. were evaluated for memory-enhancing activity against scopolamine-induced amnesia using elevated plus maze and step down paradigms. Effect on acetylcholinesterase activity in mice brain was also evaluated. Scopoletin and scopolin, in both the paradigms, significantly and dose dependently attenuated the scopolamine-induced amnesic effect. Furthermore, these compounds at 10 and 15 mg/kg exhibited activity comparable to that of standard drug, donepezil. The compounds also exhibited significant acetylcholinesterase inhibitory activity.

DHARA ID: D055347 Pubmed ID: 25828605


Access to Full Paper Not Available

Replica Louis vuitton Belts Replica Louis vuitton Handbags Replica Louis vuitton Backpack Replica Louis vuitton Capucines Bags Imitazioni Louis vuitton Borse Imitazioni Louis vuitton Cinture Imitazioni Louis vuitton Occhiali Replica Louis vuitton Geldb?rsen Replica Louis vuitton Gürtel Replica Louis vuitton Schmuck Replica Louis vuitton Schal Imitation Louis vuitton Bijoux Imitation Louis vuitton Ceinture Imitation Louis vuitton Chaussures Imitation Louis vuitton Foulard namaak Louis vuitton Gordels namaak Louis vuitton Handtassen namaak Louis vuitton Portemonnees namaak Louis vuitton Schoenen Replica Louis vuitton Bolsos Replica Louis vuitton Billeteras Replica Louis vuitton Cinturones Dior Replica Hermès Replica Yves Saint Laurent Replica Goyard Replica Imitation Louis Vuitton Imitation Hermès Imitation Dior Imitation Yves Saint Laurent Imitazioni Bottega Veneta Borse Imitazioni Delvaux Borse Imitazioni Goyard Borse Replica Taschen Replica Louis Vuitton Replica Hermès Replica Dior Replica Bottega Veneta tassen Replica Chloé tassen Replica Delvaux tassen Replica Goyard tassen imitacion Louis Vuitton imitacion Louis Vuitton imitacion Hermès imitacion Dior Replica Miu Miu Replica Prada Replica Yves Saint Laurent Replica Chanel Replica Gucci Replica Hermès Replica Miu Miu Réplique Chanel Réplique Hermès Réplique Miu Miu Imitazioni Chanel Imitazioni Hermès Imitazioni Miu Miu imitacion Bolso Yves Saint Laurent imitacion Hermes imitacion Chanel imitacion Gucci Gucci Replica Hermes Replica

Copyright | Disclaimer | Feedback | Updates | Contact
Developed and maintained by AVP Research Foundation (Formerly AVT Institute for Advanced Research), 136/137, Trichy Road, Ramanathapuram, Coimbatore - 641045, Tamil Nadu, India
Funded by Central Council for Research in Ayurvedic Sciences, Dept. of AYUSH, Ministry of Health and Family Welfare, Government of India, New Delhi