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DHARA is an online index of articles on Ayurveda published in research journals worldwide.
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Bioscience, biotechnology, and biochemistry
2006
Nov
;
(11)
:0
An anti-estrogenic lignan glycoside, tracheloside, from seeds of Carthamus tinctorius.
Yoo HH
,
Park JH
,
Kwon SW
Abstract
The lignan glycoside, tracheloside, was isolated from seeds of Carthamus tinctorius (Compositae) as an anti-estrogenic principle against cultured Ishikawa cells by employing a bioassay-linked HPLC-ELSD method. Tracheloside significantly decreased the activity of alkaline phosphatase (AP), an estrogen-inducible marker enzyme, with an IC(50) value of 0.31 microg/ml, a level of inhibition comparable to that of tamoxifen (IC(50) = 0.43 microg/ml).
DHARA ID:
D051285
Pubmed ID:
17090940
Access to Full Paper Not Available
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