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DHARA is an online index of articles on Ayurveda published in research journals worldwide.
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Phytomedicine : international journal of phytotherapy and phytopharmacology
2002
Dec
;
(8)
:0
Tribulosin and beta-sitosterol-D-glucoside, the anthelmintic principles of Tribulus terrestris.
Deepak M
,
Dipankar G
,
Prashanth D
,
Asha MK
,
Amit A
,
Venkataraman BV
Abstract
Successive extracts of Tribulus terrestris prepared using petroleum ether, chloroform, 50% methanol and water were tested for anthelmintic activity in-vitro using the nematode Caenorhabditis elegans. The activity could be detected only in 50% methanol extract which on further bioactivity guided fractionation and chromatographic separation yielded a spirostanol type saponin, tribulosin and beta-sitosterol-D-glucoside. Both the compounds exhibited anthelmintic activity with ED50 of 76.25 and 82.50 microg/ml respectively.
DHARA ID:
D050968
Pubmed ID:
12587699
Access to Full Paper Not Available
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