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DHARA is an online index of articles on Ayurveda published in research journals worldwide.
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Phytochemistry
2006
Jun
;
(11)
:0
Immunosuppressive diacetylenes, ceramides and cerebrosides from Hydrocotyle leucocephala.
Ramos F
,
Takaishi Y
,
Kawazoe K
,
Osorio C
,
Duque C
,
Acuña R
,
Fujimoto Y
,
Sato M
,
Okamoto M
,
Oshikawa T
,
Ahmed SU
Abstract
Three C-17 diacetylenic compounds (1-3), one monoterpenoid (4), seven ceramides (leucoceramides A-G, 5a-g), six cerebrosides (leucocerebrosides A-F, 6a-f) and nine known compounds were isolated from the methanolic extract of Hydrocotyle leucocephala. Their structures were established by spectroscopic methods. The isolated compounds 1-3, 5a-g, 6a-f and 7 were shown to be active in the lipopolysaccharide (LPS) induced cytokine production assay for IL-10, IL-12, and TNF-alpha.
DHARA ID:
D046971
Pubmed ID:
16631830
Access to Full Paper Not Available
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