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DHARA is an online index of articles on Ayurveda published in research journals worldwide.
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Phytotherapy Research : PTR
2006
Jan
;
(1)
:0
Antidiarrhoeal evaluation of Aegle Marmelos (Correa) Linn. root extract.
Mazumder R
,
Bhattacharya S
,
Mazumder A
,
Pattnaik AK
,
Tiwary PM
,
Chaudhary S
Abstract
A study was undertaken to evaluate the in vitro and in vivo antidiarrhoeal potential of chloroform extract of the root of Aegle marmelos (Correa) Linn. The in vitro activity was determined by agar dilution and disc diffusion techniques. The extract was studied in vivo in rats. Of the 35 tested pathogenic diarrhoea causing strains, the extract was found to be mostly active against the strains of Vibrio cholerae, followed by Escherichia coli and Shigella spp. The in vitro activity was found to be comparable to that of ciprofloxacin. Further, Aegle marmelos root extract (AMRE) treated animals showed significant inhibitory activity against castor oil-induced diarrhoea. The results so obtained thus established the efficacy of AMRE as an effective antidiarrhoeal agent.Copyright 2006 John Wiley & Sons, Ltd.
DHARA ID:
D036904
Pubmed ID:
16397850
Access to Full Paper Not Available
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