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DHARA is an online index of articles on Ayurveda published in research journals worldwide.
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Science (New York, N.Y.)
2003
Mar
;
(5614)
:0
Accumulation of phosphorylated repressor for gibberellin signaling in an F-box mutant.
Sasaki A
,
Itoh H
,
Gomi K
,
Ueguchi-Tanaka M
,
Ishiyama K
,
Kobayashi M
,
Jeong DH
,
An G
,
Kitano H
,
Ashikari M
,
Matsuoka M
Abstract
Gibberellin (GA) regulates growth and development in plants. We isolated and characterized a rice GA-insensitive dwarf mutant, gid2. The GID2 gene encodes a putative F-box protein, which interacted with the rice Skp1 homolog in a yeast two-hybrid assay. In gid2, a repressor for GA signaling, SLR1, was highly accumulated in a phosphorylated form and GA increased its concentration, whereas SLR1 was rapidly degraded by GA through ubiquitination in the wild type. We conclude that GID2 is a positive regulator of GA signaling and that regulated degradation of SLR1 is initiated through GA-dependent phosphorylation and finalized by an SCF(GID2)-proteasome pathway.
DHARA ID:
D024742
Pubmed ID:
12649483
Access to Full Paper Not Available
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