Home
|
About
|
Quick Start
|
FAQ
Beta Version 0.1
DHARA is an online index of articles on Ayurveda published in research journals worldwide.
Users Online:
251
Unfiltered
Classified Search
Enter Keyword Below :
Advanced
Nature
2005
Apr
;
(7036)
:0
The genome sequence of the rice blast fungus Magnaporthe grisea.
Dean RA
,
Talbot NJ
,
Ebbole DJ
,
Farman ML
,
Mitchell TK
,
Orbach MJ
,
Thon M
,
Kulkarni R
,
Xu JR
,
Pan H
,
Read ND
,
Lee YH
,
Carbone I
,
Brown D
,
Oh YY
,
Donofrio N
,
Jeong JS
,
Soanes DM
,
Djonovic S
,
Kolomiets E
,
Rehmeyer C
,
Li W
,
Harding M
,
Kim S
,
Lebrun MH
,
Bohnert H
,
Coughlan S
,
Butler J
,
Calvo S
,
Ma LJ
,
Nicol R
,
Purcell S
,
Nusbaum C
,
Galagan JE
,
Birren BW
Abstract
Magnaporthe grisea is the most destructive pathogen of rice worldwide and the principal model organism for elucidating the molecular basis of fungal disease of plants. Here, we report the draft sequence of the M. grisea genome. Analysis of the gene set provides an insight into the adaptations required by a fungus to cause disease. The genome encodes a large and diverse set of secreted proteins, including those defined by unusual carbohydrate-binding domains. This fungus also possesses an expanded family of G-protein-coupled receptors, several new virulence-associated genes and large suites of enzymes involved in secondary metabolism. Consistent with a role in fungal pathogenesis, the expression of several of these genes is upregulated during the early stages of infection-related development. The M. grisea genome has been subject to invasion and proliferation of active transposable elements, reflecting the clonal nature of this fungus imposed by widespread rice cultivation.
DHARA ID:
D022336
Pubmed ID:
15846337
Access to Full Paper Not Available
Copyright
|
Disclaimer
|
Feedback
|
Updates
|
Contact
Developed and maintained by AVP Research Foundation (Formerly AVT Institute for Advanced Research), 136/137, Trichy Road, Ramanathapuram, Coimbatore - 641045, Tamil Nadu, India
Funded by Central Council for Research in Ayurvedic Sciences, Dept. of AYUSH, Ministry of Health and Family Welfare, Government of India, New Delhi