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DHARA is an online index of articles on Ayurveda published in research journals worldwide.
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Planta Medica
2004
Jul
;
(7)
:0
Guineensine, an Acyl-CoA: cholesterol acyltransferase inhibitor, from the fruits of Piper longum.
Lee SW
,
Rho MC
,
Nam JY
,
Lim EH
,
Kwon OE
,
Kim YH
,
Lee HS
,
Kim YK
Abstract
Bioactivity-guided fractionations for ACAT inhibitor led to the isolation of guineensine from the CHCl (3) extract of Piper longum. Its structure was identified by spectroscopic means (IR, UV, MS and NMR). Guineensine inhibited ACAT activity in a dose-dependent manner with an IC (50) value of 3.12 micro M.
DHARA ID:
D015178
Pubmed ID:
15254860
Access to Full Paper Not Available
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