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DHARA is an online index of articles on Ayurveda published in research journals worldwide.
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Journal of Natural Products
2004
Jul
;
(7)
:0
Chemical constituents of Millettia taiwaniana: structure elucidation of five new isoflavonoids and their cancer chemopreventive activity.
Ito C
,
Itoigawa M
,
Kojima N
,
Tokuda H
,
Hirata T
,
Nishino H
,
Furukawa H
Abstract
We describe the isolation and identification of five new isoflavonoids, millewanins A (1), B (2), C (3), D (4), and E (5), together with six known isoflavonoids and three rotenoids, from the stems of Millettia taiwaniana collected in Japan. The major component, auriculasin (6), exhibited significant inhibitory effect on mouse skin tumor promotion in an in vivo two-stage carcinogenesis test. The results of the present investigation indicate that 6 might be a valuable antitumor promoter.
DHARA ID:
D014321
Pubmed ID:
15270565
Access to Full Paper Not Available
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